Fig. 3: G100–ZVex combination induces durable anti-tumor immune responses. | npj Vaccines

Fig. 3: G100–ZVex combination induces durable anti-tumor immune responses.

From: Intratumoral immune activation with TLR4 agonist synergizes with effector T cells to eradicate established murine tumors

Fig. 3

Female C57BL/6 mice (n = 10–16/group) treated with the G100–ZVex combination and had complete tumor regression were re-challenged with a B16/OVA or b B16 cells, inoculated in the opposite flank of the original tumor challenge. Tumor size and c survival were monitored and recorded at least 2–3 times weekly. “Ctrl” group of mice were age-matched naïve mice, inoculated with a B16/OVA or b B16 cells. Tumor sizes were plotted as average tumor volume ± SEM. Death was recorded as a result of death defined by euthanasia criteria. Data are representative of at least 2 independent experiments (**p < 0.01, ****p < 0.0001).

Back to article page