Table 3 Number of sequence reads detected for each of the spiked viruses at the different spiking levels in the cell substrate matrix.
From: Sensitivity and breadth of detection of high-throughput sequencing for adventitious virus detection
Virus | Genome copies per cell | |||
|---|---|---|---|---|
0.01 | 0.01 | 0.001 | 0.001 | |
NIH | ||||
Adenoviridae | ||||
Adenovirus 5 | 244 | 125 | 18 | 4 |
Adenovirus 41 | 21 | 8 | 0 | 0 |
Flaviviridae | ||||
Bovine Viral Diarrhea Virus | 1014 | 1096 | 11 | 12 |
Herpesviridae | ||||
Herpes Simplex Virus Type 1 | 58 | 17 | 0 | 0 |
Simian Cytomegalovirus | 449 | 386 | 2 | 32 |
Orthomyxoviridae | ||||
Influenza A Virus | 0* | 0* | 0* | 0* |
Paramyxoviridae | ||||
Bovine Parainfluenza Virus Type 3 | 627 | 512 | 25 | 11 |
Measles Morbillivirus | 43 | 45 | 0 | 0 |
Mumps Virus | 181 | 253 | 2 | 4 |
Picornaviridae | ||||
Coxsackievirus A16 | 10 | 9 | 0 | 0 |
Coxsackievirus B3 | 55 | 106 | 0 | 0 |
Echovirus 11 | 110 | 86 | 0 | 0 |
Rhinovirus 2 | 6 | 20 | 0 | 0 |
Polyomaviridae | ||||
Simian Virus 40 | 48 | 29 | 1 | 0 |
Rhabdoviridae | ||||
Vesicular Stomatitis Virus | 580 | 674 | 5 | 7 |
Togaviridae | ||||
Rubella Virus | 130 | 41 | 0 | 0 |
SP | ||||
Bornaviridae | ||||
Human Borna Disease Virus | 14 | 10 | 0 | 9 |
Coronaviridae | ||||
Bovine Coronavirus | 35 | 41 | 0 | 2 |
Herpesviridae | ||||
Human Cytomegalovirus | 12,990 | 13,089 | 554 | 551 |
Parvoviridae | ||||
Minute Virus of Mice | 0* | 14* | 0* | 0* |
Porcine Parvovirus | 5428 | 4932 | 327 | 214 |
Reoviridae | ||||
Reovirus Type 3 | 0* | 0* | 0* | 0* |
