Table 2 Major components of fungal cell walls.

From: Vaccines for human fungal diseases: close but still a long way to go

Fungal cell wall components

Structure composition

Location

Chitin

Homopolymer of N-Acetylglucosamine that provides structural stability

Inner portion of cell wall, adjacent to the plasma membrane

Chitosan

Deacetylated chitin

Inner portion of cell wall, intermingled with chitin

β-glucan

Homopolymers of glucose with β-1,3-glucans forming the scaffold and β-1,6-glucans forming the branches

Middle portion of cell wall, between chitin and mannans

Mannoprotein

Mannose chains of varying lengths and configurations added to fungal proteins via N-linkages or O-linkages

From anchorage in plasma membrane to outer portion of cell wall