Table 3 Amino acid mutations in the RBD region of SARS-CoV-2 variants of concern.

From: Scientific rationale for developing potent RBD-based vaccines targeting COVID-19

WHO Label

Pango lineage

Mutations in RBD region

Alpha

B.1.1.7

N501Y, (E484K*), (S494P*)

Beta

B.1.351, B.1.351.2, B.1.351.3

K417N, E484K, N501Y

Delta

B.1.617.2, AY.1, AY.2, AY.3

L452R, T478K, (K417N*)

Gamma

P.1, P.1.1, P.1.2

K417T, E484K, N501Y

  1. Parentheses and * indicate the mutation is found in some sequences but not all. Information adapted from https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-info.html#Concern, current as of 13 August 2021.
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