Fig. 1: Antibody levels following vaccination with Pfs25-EPA or Pfs230D1-EPA with ALFQ adjuvant.

Serum ELISA units of Rhesus monkeys (n = 5) vaccinated with Pfs25-EPA (a) or Pfs230D1-EPA (b) formulated with ALFQ adjuvant. Sera from each animals were analyzed in triplicate, and the y-axis represents the geometric mean of ELISA units with 95% confidence interval. Black arrows indicate the days of vaccination; red arrows indicate the days of SMFA. EU for the high-dose group of Pfs230D1-EPA was significantly higher than that for the low-dose group; p = 0.032 by GEE analysis.