Fig. 4: A third vaccination of Pfs230D1-EPA induces durable functional activity. | npj Vaccines

Fig. 4: A third vaccination of Pfs230D1-EPA induces durable functional activity.

From: Malaria transmission-blocking conjugate vaccine in ALFQ adjuvant induces durable functional immune responses in rhesus macaques

Fig. 4

a transmission reducing activity, by group, 16 weeks (d434) and 40 weeks (d600) after 3rd vaccination. Each data point represents TRA from one monkey; red lines denote arithmetic mean TRA. b nonlinear 4-parameter curve fit of log (titer) vs TRA. Antibody titers shown account for dilution of immune monkey sera in the feeding assay. An IC50 was estimated for using a 4-parameter curve fit of the log(titer) vs %TRA for each monkey of the d434 and d600 SMFA data combined.

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