Fig. 5: Avidity increased with repeated vaccinations. | npj Vaccines

Fig. 5: Avidity increased with repeated vaccinations.

From: Malaria transmission-blocking conjugate vaccine in ALFQ adjuvant induces durable functional immune responses in rhesus macaques

Fig. 5

a Antibody avidity, presented as dissociation constant KD, of sera from animals immunized with high (blue) or low (red) dose of the Pfs230D1-EPA conjugate at different time points during the study. Group size = 5. Each point represents the mean value for the group and error bars represent the standard deviation. b Correlation between antibody avidity and functional activity (%TRA) of sera from day 84, d168 and d350. Points represent KD for each monkey. Spearman r = −0.8226; p < 0.0001.

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