Fig. 5: Binding of antibodies from vaccinated sheep to P. falciparum NF54 sporozoites. | npj Vaccines

Fig. 5: Binding of antibodies from vaccinated sheep to P. falciparum NF54 sporozoites.

From: Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites

Fig. 5

Sporozoites labelled with antibodies purified from sheep injected with the different vaccines. Antibodies from sheep vaccinated with the soluble B- and B/T-cell epitope peptides and the empty BPs did not label the sporozoite surface like the monoclonal anti-NANP3 antibody (CSP; clone 2A10) that served as positive control (purple). Antibodies from sheep vaccinated with the B- and B/T-cell epitope-coated BPs labelled the sporozoite surface (purple). Empty BPs and only the anti-sheep antibody (negative controls) served as control and did not surface label sporozoites. DNA was visualised with DAPI (magenta). Scale bars, 10 µm.

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