Fig. 4: Vaccination reduces viral shedding and viral RNA load in SARS-Cov2 challenged hamsters. | npj Vaccines

Fig. 4: Vaccination reduces viral shedding and viral RNA load in SARS-Cov2 challenged hamsters.

From: Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters

Fig. 4

a Vaccination and challenge schedule. Sampling timepoints are shown by black arrows. Groups of animals (n = 4) were euthanized at 4 and 8 dpi as shown by the orange arrows. Sampling timepoints are shown by black arrows. Titers of infectious virus from various timepoints were collected and determined by TCID50 from b oral swabs, c nasal washes, d nasal turbinates, and e lungs. Error bars represent standard deviation. P value = 0.0001 (****) and 0.0003 (***).

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