Fig. 3: pWRG/VEE delivered by IM-, but not ID-, DSJI elicits anti anti-VEEV GP cellular immunity. | npj Vaccines

Fig. 3: pWRG/VEE delivered by IM-, but not ID-, DSJI elicits anti anti-VEEV GP cellular immunity.

From: A DNA vaccine targeting VEE virus delivered by needle-free jet-injection protects macaques against aerosol challenge

Fig. 3

a VEEV E1- and (b) E2-specific IFN-γ+ T cells. Peripheral blood mononuclear cells were stimulated with pools of 15-mer, overlapping peptides spanning the VEEV E1 or E2 proteins. Data represent the group mean ± SD. Statistical analysis was performed using a two-way ANOVA with Tukey’s multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.001. Circled symbols represent individual animals in VEEV-vaccinated groups that developed a fever >3 °C above baseline after VEEV aerosol challenge.

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