Fig. 1: Binding and neutralizing-antibody responses to immunization with RBD-NP and adjuvants. | npj Vaccines

Fig. 1: Binding and neutralizing-antibody responses to immunization with RBD-NP and adjuvants.

From: Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice

Fig. 1

a Study design for measuring binding and neutralizing antibodies, T cell responses, BM plasma cells, and innate responses in C57BL/6 mice. b Spike-protein binding antibody titers in serum of mice immunized with RBD-NP in various adjuvants at days 0, 7, 20, 28, and 42 post-immunization. Error bars indicate mean ± SEM. c Neutralizing-antibody titers measured by pseudovirus neutralization assays at days 20 (prime-only) and 42 (prime-boost). P-values: * denotes p < 0.0332, **p < 0.0021, ***p < 0.0002, and ****p < 0.0001.

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