Fig. 2: Bone marrow plasma cell responses to immunization with RBD-NP and adjuvants. | npj Vaccines

Fig. 2: Bone marrow plasma cell responses to immunization with RBD-NP and adjuvants.

From: Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice

Fig. 2

a Anti-spike protein IgG1 and IgG2c titers in serum measured at day 28 post-immunization. Right panel represents ratio of IgG1 to IgG2c titers. b Pooled ELISPOT results from 2 independent experiments with n = 4 mice per experiment. Total IgG, IgG1, and IgG2c-producing bone marrow plasma cells were quantified at day 33 post-immunization. P-values: * denotes p < 0.0332, **p < 0.0021, ***p < 0.0002, and ****p < 0.0001. Error bars indicate mean ± SEM in all panels.

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