Fig. 5: Humoral immune responses to co-administration of pre-F-NP and Gcc-Foldon in RSV-primed cynomolgus macaques. | npj Vaccines

Fig. 5: Humoral immune responses to co-administration of pre-F-NP and Gcc-Foldon in RSV-primed cynomolgus macaques.

From: Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle

Fig. 5

a RSV A2 neutralizing titers (PRNT50), b RSV F-specific IgG ELISA titers, c RSV Ga-specific IgG ELISA titers, and d RSV Gb-specific IgG ELISA titers following intramuscular vaccination of six cynomolgus macaques/group without adjuvant or with: AlPO4 or AF03 on day 101 and day 129 (*p value <0.01). GMT geometric mean titers, SD geometric standard deviation; dotted lines = limit of quantification; + = RSV infection on day 0; arrows = immunizations. All statistical values were performed using Student’s t-test.

Back to article page