Fig. 2: Results of CHMIs to assess VE during Verification.

a First CHMI at 3 weeks (top row) and second CHMI at 9–10 weeks (bottom row) of the individual volunteers. The black indicates no parasitemia (protected); the white represents parasitaemia (not protected). b Kaplan-Meier plots for heterologous CHMIs with Pf7G8. Five of 6 vaccinees were protected at 3 weeks and at 9–10 weeks. Six of 6 CHMIs with PfSPZ Challenge (7G8) in the controls resulted in parasitemia (infected). c Kaplan-Meier plots for homologous CHMIs with PfNF54. Four of 6 vaccinees were protected at 3 weeks and 5/6 were protected at 9–10 weeks. Five of 6 CHMIs with PfSPZ Challenge (NF54) in the controls resulted in parasitemia (infected).