Fig. 5: Impact of ORF150 in vivo. | npj Vaccines

Fig. 5: Impact of ORF150 in vivo.

From: Development of an attenuated vaccine against Koi Herpesvirus Disease (KHVD) suitable for oral administration and immersion

Fig. 5

Direct impact of ORF150 deletion on virulence of KHV. Carp were infected by immersion with 105 TCID50/mL of engineered KHV-T recombinants possessing a complete deletion of ORF150 (purple line), the naturally occurred partial deletion of ORF150 inserted into wildtype background (blue line), or challenge infection wildtype KHV-T (orange line). Shown are the survival rates after wild-type challenge at day 35 p.i.

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