Table 1 Vaccine dosages.

From: Needle-free, spirulina-produced Plasmodium falciparum circumsporozoite vaccination provides sterile protection against pre-erythrocytic malaria in mice

Delivery route

Composition of spirulina+

Final concentration of spirulina

Treatment volume per dose

Amount of spirulina per dose

Est. percent of vaccine construct

Dose of vaccine per treatment

Oral

Unpurified

50 mg/mL

200 µL

10 mg

0.8–1% of whole dried biomass

80–100 µg

Intranasal

Unpurified

50 mg/mL

50 µL

2.5 mg

0.8–1% of whole dried biomass

20–25 µg

Intranasal

Extract

7.8 mg/mL

50 µL

390 µg

4% of total soluble protein

15.7 µg*

17.4 µg**

  1. +Unpurified = whole biomass powder resuspended in HBSS with 10% Montanide; Extract = total soluble protein in HBSS with 10% Montanide.
  2. *Doses with* or without** Montanide.