Table 3 Predicted versus observed aggregate vaccine effectiveness for the PCV7 serotypes in PCV13.

From: Predicting vaccine effectiveness against invasive pneumococcal disease in children using immunogenicity data

 

Vaccine effectiveness Median (95% CI)

United Kingdom

Australia

Germany

Predicted

93% (20–100)

71% (3–97)

91% (5–100)

Observed

90% (34–98)a

70% (−8–92)b

90% (57–98)c

  1. CI confidence interval.
  2. aData are from Andrews et al.10.
  3. bData are from Jayasinghe et al.11.
  4. cData are from Weinberger et al.12.
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