Fig. 3: Neutralizing antibody titres and comparisons between groups.

Correlations between half-maximal log10 inhibitory concentrations (IC50) of antibodies required to neutralize rVSV-S infection of Vero cells vs normalized a anti-RBD IgG or b anti-FLS IgG OD levels after infection (blue chevron) and PV1 (teal square) in the asymptomatic/mild and c, d moderate/severe groups are depicted. The relationship between days post infection or days post symptom onset at collection (DPI/DPSO) is illustrated in (e). Neutralization capacity of Ab activity acquired f post infection and g PV1 was compared between the asymptomatic/mild (yellow circle) and moderate/severe (purple square) groups. P values in f, g were calculated using the Mann–Whitney U-test. Red lines bisecting groups represent median (solid) with IQR (dotted).