Fig. 2: Passive transfer of hyper-immune sera to naïve mice. | npj Vaccines

Fig. 2: Passive transfer of hyper-immune sera to naïve mice.

From: B cells oppose Mycoplasma pneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs

Fig. 2

A Histopathologic scoring of lungs from mice intranasally inoculated with Lipid-associated Membrane Protein-induced (LAMP), delipidated Lipid-associated Membrane Protein-induced (dLAMP) or naïve-mouse (sham) serum at high (Hi) or low (Lo) concentration and challenged with M. pneumoniae. Data were compared by Kruskal–Wallis test with Dunn’s post-hoc test used for multiple comparisons. B Bacterial recoveries from the lungs of mice intranasally inoculated with vaccine-induced or naïve-mouse (Sham) serum at high or low concentration and challenged with M. pneumoniae. Data are displayed as median with interquartile range, and were compared by Kruskal–Wallis test with Dunn’s post-hoc test used for multiple comparisons. C Histopathologic scoring of lungs from mice intraperitoneally inoculated with vaccine-induced or naïve-mouse (sham) serum and challenged with M. pneumoniae. Data were compared by Kruskal–Wallis test with Dunn’s post-hoc test used for multiple comparisons. D Bacterial recoveries from the lungs of mice intraperitoneally inoculated with vaccine-induced or naïve-mouse (Sham) serum and challenged with M. pneumoniae. Data are displayed as median with interquartile range, and were compared by Kruskal–Wallis test with Dunn’s post-hoc test used for multiple comparisons.

Back to article page