Fig. 6: Immunization of BALB/c mice with ΔM27-MCMV raises strong MCMV-specific FcγR-activating IgG responses. | npj Vaccines

Fig. 6: Immunization of BALB/c mice with ΔM27-MCMV raises strong MCMV-specific FcγR-activating IgG responses.

From: Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus

Fig. 6

BALB/c mice were infected i.p. with wt-MCMV or ΔM27-MCMV. At 3, 7, 14, and 21 dpi, serum samples were collected. Fcγ receptor-activating capacity was quantified from sera by mIL-2 ELISA using a surrogate assay as described in the M&M section and in reference 37. The mean values as well as the values of individual mice (n = 4 per group) are shown. a Activation assay for mFcγRI. b Activation assay for mFcγRII. c Activation assay for mFcγRIII. d Activation assay for mFcγRIV.

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