Fig. 5: Cellular immune responses in BALB/c mice immunized with mRNA vaccine. | npj Vaccines

Fig. 5: Cellular immune responses in BALB/c mice immunized with mRNA vaccine.

From: Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa

Fig. 5

a Image of the Elispot assay plate and the spot counts of IFNγ-producing T cells detected by Elispot. b The percentages of IFNγ-producing CD4+ and CD8 + T cells detected by intracellular cytokine staining. c The percentages of IL-2-producing CD4+ and CD8 + T cells detected by intracellular cytokine staining. d The percentages of IL-4-producing CD4+ and CD8 + T cells detected by intracellular cytokine staining. Mice in each group n = 8. One-way ANOVA was performed (ns non-significance, *P < 0.05, **P < 0.01, ***P < 0.001). Data are presented as means ± SEM.

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