Fig. 7: Bacterial colonization of organs following the challenge in mRNA-immunized mouse burn models. | npj Vaccines

Fig. 7: Bacterial colonization of organs following the challenge in mRNA-immunized mouse burn models.

From: Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa

Fig. 7

a Bacterial counts per gram of mice skin after challenge with standard strain PAO1 10xLD50 in burn model. b Bacterial counts per gram of mice lung after challenge with standard strain PAO1 10xLD50 in burn model. c Bacterial counts per gram of mice liver after challenge with standard strain PAO1 10xLD50 in burn model. d Bacterial counts per gram of mice kidney after challenge with standard strain PAO1 10xLD50 in burn model. e Bacterial counts per gram of mice spleen after challenge with standard strain PAO1 10xLD50 in burn model. f Bacterial counts per gram of mouse skin after challenge with clinical strain PA257 10xLD50 in a burn model. g Bacterial counts per gram of mouse lung after challenge with clinical strain PA257 10xLD50 in a burn model. h Bacterial counts per gram of mouse liver after challenge with clinical strain PA257 10xLD50 in a burn model. i Bacterial counts per gram of mouse kidney. after challenge with clinical strain PA257 10xLD50 in a burn model. j Bacterial counts per gram of mouse spleenafter challenge with clinical strain PA257 10xLD50 in a burn model. Mice in each group n = 8. One-way ANOVA was performed (ns non-significance, *P < 0.05, **P < 0.01, ***P < 0.001). Data are presented as means ± SEM.

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