Table 4 Summary of investment costs.

From: A Strep A vaccine global demand and return on investment forecast to inform industry research and development prioritization

 

Pharma MNC investment (millions, USD)

DCVM investment (millions, USD)

Preclinical development

$26

$8

Phase 1

$20

$10

Phase 2

$40

$25

Phase 3

$200

$70

Process development

$12

$10

Regulatory activities

$5

$2

Building manufacturing capacity

$150

$40

Post-marketing activities

$75

$20

Total

$528

$185

Risk-adjusted total

$979

$372

  1. Investment costs for each stage of Strep A vaccine research and development.