Table 1 Statistical analysis of body weight changes in mice immunized with unconjugated and nanoparticle-conjugated N1 NC13 after challenge with H1N1 Bel/09

From: Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge

H1N1 Bel/09

Adj. p-value1

Weight loss phase (day 0–4)

1) N1 NC13-Mi3 vs. N1 NC132

0.006

2) 1 vs. 0.1 µg N1 NC13

1

3) 1 vs. 0.1 µg N1 NC13-Mi3

1

Recovery phase (day 4–6)

1) N1 NC13-Mi3 vs. N1 NC132

0.007

2) 1 vs. 0.1 µg N1 NC13

0.22

3) 1 vs. 0.1 µg N1 NC13-Mi3

1

  1. 1Adjusted p-values for differences between groups shown in Fig. 4b in two phases of infection based on the piecewise linear mixed model output described in Supplementary Note 1.
  2. 2Comparison between mice immunized with N1-Mi3 and N1, combining the data from mice immunized with 0.1 and 1 µg of the antigens.
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