Table 3 Statistical analysis of body weight changes in mice immunized with different nanoparticles preparations after challenge with H1N1 Bel/09 or H3N2 X31

From: Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge

Weight loss phase (days 0–4)

Adj. p-valuea1

H1N1 Bel/09

1) N1-Mi3 vs. N1-N2-Mi3 Mosaic

0.001

2) N1-Mi3 vs. N1/N2 Mix

0.145

3) N1/N2-Mi3 Mix vs. N1-N2-Mi3 Mosaic

0.353

H3N2 X31

1) N2-Mi3 vs. N1-N2-Mi3 Mosaic

0.992

2) N2-Mi3 vs. N1/N2 Mix

0.002

3) N1/N2-Mi3 Mix vs. N1-N2-Mi3 Mosaic

0.472

  1. 1Adjusted p-values for differences between groups in the initial weight loss phase of infection based on the piecewise linear mixed model output described in Supplementary Note 1.
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