Fig. 2: Differential TBEV-specific antibody responses following vaccination, TBE or VBT TBE. | npj Vaccines

Fig. 2: Differential TBEV-specific antibody responses following vaccination, TBE or VBT TBE.

From: Tick-borne encephalitis vaccine breakthrough infections induce aberrant T cell and antibody responses to non-structural proteins

Fig. 2

A TBEV-specific IgG titer in serum samples obtained after vaccination, infection or VBT infection. B Vaccination-, infection- or VBT infection-induced virus neutralizing titers (VNT100). C, D TBEV EDIII- and NS1-specific serum antibodies in vaccinees, unvaccinated patients, and VBTs. Horizontal lines indicate the mean with standard errors of the mean (SEM). Dashed lines indicate cut-off values for positive responses as detailed in the methods section. Two-tailed Kruskal–Wallis test or One-way ANOVA with multiple comparison test was performed for comparisons of groups. *p < 0.05, ***p < 0.001, ****p < 0.0001.

Back to article page