Table 1 Prediction of the antigenicity, allergenicity, and toxicity of AcdA portions

From: A rationally designed antigen elicits protective antibodies against multiple nosocomial Gram-positive pathogens

 

VaxiJen score

AllerTop 2.0

AllergenFP 1.0

ToxinPred

AdcA

0.55

Non-allergen

Non-allergen

Non-toxic

ZnuA

0.46

Non-allergen

Non-allergen

Non-toxic

ZinT

0.69

Likely allergen

Non-allergen

Non-toxic

EH-motif

1.59

Non-allergen

Non-allergen

Non-toxic

  1. VaxiJen threshold for antigenicity is set to 0.4.