Table 5 Establishment of 1st WHO International Standards for HPV antibodies by the Expert Committee on Biological Standardization in October 2022

From: WHO International Standards for antibodies to HPV6 HPV11 HPV31 HPV33 HPV45 HPV52 and HPV58

1st WHO International Standard for Human Papillomavirus (HPV)

NIBSC Product code

unitage (IU/ampoule)

unitage (IU/mL) when reconstituted as directed in 0.25 mL dH2O

Approximate number of ampoules available from NIBSC as of Oct 2022

Type 6 antibodies

19/298

7

28

2500

Type 11 antibodies

20/174

6

24

1000

Type 31 antibodies

20/176

3

12

600

Type 33 antibodies

19/290

8

32

3000

Type 45 antibodies

20/178

2

8

700

Type 52 antibodies

19/296

14

56

900

Type 58 antibodies

19/300

20

80

2400

  1. NIBSC HPV standards are available from the MHRA (https://nibsc.org/products/brm_product_catalogue/sub_category_listing.aspx?category=Vaccines&subcategory=Human%20Papillomavirus).