Fig. 4: H10ssF vaccination elicited neutralizing antibodies against H10N8 A/Jiangxi-Donghu/346/2013.

The geometric mean IC50 neutralizing antibody titers (GMT) and 95% CI of all 60 mcg H10ssF recipients are shown in black, with individual participants’ values in red or blue based on their age group. The dotted line indicates the assay LOD. Brackets indicate two time points that are significantly different from each other with the p value noted above the line. When the significance between a timepoint and baseline is p ≤ 0.001, this is noted by a symbol above the later timepoint. When LOD imputation with zero produced a different p value than imputation with half LOD, results are reported as p ≤ x, where x is the least significant p value resulting from the two test methods.