Fig. 4: Protective efficacy against RSV infection.
Balb/c mice were immunized as described before. a, b 37 days after boost immunization, mice were challenged with 5 ×106 PFU RSV-A. All animals were monitored daily for body weight (a) and every second day for oxygen saturation (b). Time points show group´s mean values with +SEM; all groups n = 6. Data were analysed by two-way ANOVA followed by Dunnett´s multiple comparison test. Statistically significant differences were indicated among naive and vaccinated groups; (o: statistically significant worse than naive; +: statistically significant better than naive).
