Fig. 2: Formulation of Modi-2 peptides with SNAPvax technology. | npj Vaccines

Fig. 2: Formulation of Modi-2 peptides with SNAPvax technology.

From: Modi-2 a vaccine stimulating CD4 responses to homocitrullinated self epitopes as therapy for solid cancers

Fig. 2

A DLS histograms showing the size of particles of Modi-2 peptides in CpG/MPLA or TLR7/8 formulation. Each colour represents a different repeat measurement. B A schematic figure of the SNAPvax (Self-assembling Nanoparticles based on Amphiphilic Peptides) platform. C DLS histograms showing the size of nanoparticles of Modi-2 SNAPvax formulations in different buffers. The particle size is shown in nanometer22 ± standard deviation (SD). Each colour represents a different repeat measurement. At least 3 replicate assays were performed. D Transmission electron micrograph images of Modi-2 SNAPvax formulations in Histidine or Tris buffers. E UPLC-PDA chromatogram showing distinct peaks for each of Modi-2 peptides in the SNAPvax formulation. Images in (B) from Barinthus Biotherapeutics.

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