Fig. 6: Human tumours express Modi-2 target antigens. | npj Vaccines

Fig. 6: Human tumours express Modi-2 target antigens.

From: Modi-2 a vaccine stimulating CD4 responses to homocitrullinated self epitopes as therapy for solid cancers

Fig. 6

Colorectal (CRC) and breast (BR) tumour microarrays stained by immunohistochemistry for vimentin, cytokeratin 8, aldolase A, BiP and MPO using antigen specific antibodies and homocitrullination using an anti-carbamyl antibody. A representative staining images of low, moderate and high staining. B Data shown as H-score for normal or normal adjacent tissue (NAT) compared to tumour tissue on the CRC TMAs. C Data shown as H-score for tumour tissue on the BR TMAs.

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