Fig. 5: Multivariate gene log2 fold change (LFC) responses at Day 8 and Day 36 that best predicted the magnitude of peak log2 virus neutralization assay (VNA) antibody titer post-second vaccination. | npj Vaccines

Fig. 5: Multivariate gene log2 fold change (LFC) responses at Day 8 and Day 36 that best predicted the magnitude of peak log2 virus neutralization assay (VNA) antibody titer post-second vaccination.

From: A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose

Fig. 5

The bar plots show the estimated linear regression coefficients for genes selected by the best model. Scatterplots that summarize the marginal association between gene expression fold change and peak VNA response, including locally estimated scatterplot smoothing (loess) trend lines, are shown for the top six genes selected by each model.

Back to article page