Fig. 1: Schematic representation of the molecular structure of Clec9a. | npj Vaccines

Fig. 1: Schematic representation of the molecular structure of Clec9a.

From: Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials

Fig. 1

The extracellular C-type lectin-like domain (CTLD) is extensively glycosylated, as indicated by the green circles; the neck region serves as a junction between the CTLD and the transmembrane domain; and the intracellular cytoplasmic tail harbors potential signaling motifs, including a hemITAM motif, which is crucial for downstream signaling pathways. Created with BioRender.com (Agreement number: WE26UDX16L).

Back to article page