Fig. 2: Protection by reduction of organ virus load. | npj Vaccines

Fig. 2: Protection by reduction of organ virus load.

From: Differential efficacy of first licensed western vaccines protecting without immunopathogenesis Wuhan-1-challenged hamsters from severe COVID-19

Fig. 2

Virus load in infected hamsters determined (A) by titration of live virus titers in lung tissue or B, C quantification of viral RNA by qRT-PCR in B lung tissue or C bronchoaveloar lavage (BAL) 4 days post infection. D Quantification of IL-4 (left), IL-13 (middle), and IFN-γ (right) expression relative to RPL18 housekeeping gene by qRT-PCR of mRNAs to determine the bias of reactive T cells in vaccinated animals after SARS-CoV-2 infection. Single data points indicate individual animals. The horizontal bar denotes the median of each group. For statistical analysis, ordinary one-way ANOVA was applied with Tukey’s multiple comparisons test. ns not significant (p > 0.05), *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

Back to article page