Fig. 6: Daily clinical scores of pigs.

Cumulative clinical scores based on clinical signs observed daily for pigs immunised and boosted with GΔBDKE-CmutQ96R/K108D at different doses a 103 (Group X), b 104 (Group Y), and c 102 (Group D). d Pigs immunised (104) without a booster dose (Group C) and The clinical scores for the non-immune, challenge control groups were recorded following challenge with Georgia 2007/1 isolate, for (e) experiment 1 and (f) experiment 2. g Pigs immunised with 104.5 TCID50 dose (Group E).