Fig. 9: Multiplex cytokine profiling in overnight stimulated splenocyte cultures at 7 days post boost immunization. | npj Vaccines

Fig. 9: Multiplex cytokine profiling in overnight stimulated splenocyte cultures at 7 days post boost immunization.

From: Lipid Nanoparticle Development for A Fluvid mRNA Vaccine Targeting Seasonal Influenza and SARS-CoV-2

Fig. 9

Mouse splenocytes were stimulated with 10μg/mL (A) HA(H1N1) or (B) spike (Wuhan strain) for 18 h. Comparison between immunized groups vs PBS control group was performed using a Kruskal–Wallis test with Dunn’s multiple groups correction. The statistical analysis for all 12 cytokines is shown in Table 5. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001. All other comparisons were non-significant. N = 5 per group.

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