Fig. 7: Co-culture of dendritic cells from mice immunized in early-life with HB-alum prime more Th2 biased T cell responses.

A Bone marrow was harvested (n = 6) from mice immunized with (B) HB-alum or (C) HB-CpG at DOL7 or DOL56. BMDCs were co-cultured with OVA-specific CD4+ T cells from DO11.10 mice. Cells were stimulated ex vivo with OVA, and secreted cytokines were measured. Data are displayed as mean ± SEM. Statistical differences were determined using the Mann–Whitney test; *p < 0.05.