Fig. 2: Designs elicit high antibody titers against target antigens in C57BL/6 mice.
From: A combined designed CSP and Pfs48/45 infection and transmission blocking vaccine for malaria
a Timeline for mouse immunization and sporozoite challenge (Created in BioRender. Dickey, T. (2025) https://BioRender.com/mcorhho). b IgG antibody titer against CSPj5c at days 21, 35 and 56. c IgG antibody titer against Pfs48/45 17-4 immunogen at days 21, 35 and 56. d IgG antibody titers against ferritin at days 21, 35, and 56. For all panels, median values and 95% confidence levels are displayed with individual values, and the p-values were calculated using the Kruskal-Wallis non-parametric test followed by Dunn’s test corrected for the three comparisons in each section of the graph.
