Fig. 2: Antibody response elicited by dendrimer peptides.

Two groups of 5 animals each were immunized on day 0 with B2T-TB2 (orange circles) or B2T (green circles) and challenged at 25 dpi (down-pointing arrows). A ELISA antibody response in sera from 15, 25, and 36 dpi. B Neutralizing antibody responses at 15, 25, and 36 dpi, determined as detailed in “Methods”. Dotted line indicates the detection limit. Numbers next to each circle indicate pig number. Horizontal lines indicate the geometric mean for each animal group. No spontaneous reactivity was observed in titers at day 0. Statistically significant differences are indicated by asterisks (*) for p < 0.05.