Fig. 4: Specific T-cell responses to B2T-TB2 and related peptides. | npj Vaccines

Fig. 4: Specific T-cell responses to B2T-TB2 and related peptides.

From: Single dose of foot-and-mouth disease peptide vaccine fully protects swine and achieves intraserotype crossed neutralization

Fig. 4

Specific T-cell responses measured by an ex vivo IFN-γ ELISPOT at 15 (A) and 25 dpi (B). IFN-γ release by PBMCs stimulated in vitro with either B2T-TB2, B2T, or with single T or B peptide epitopes. The frequency of FMDV-specific IFN-γ secreting cells was determined as detailed in Methods. The box-and-whisker plot shows each individual value as a dot, from the minimum up to the maximum value. The box extends from 25 to 75th percentiles where the dotted line represents the median. The numbers next to each symbol indicate the pig number, as in Table 1. Statistically significant differences are indicated by asterisks (*) for p < 0.05.

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