Table 2 Performance of HC-FIA with respect to clinical diagnosis or RT–qPCR (as ground truths)
From: Rapid lateral flow immunoassay for the fluorescence detection of SARS-CoV-2 RNA
Sensitivity | Specificity | Total consistency rate | κ | |||||
|---|---|---|---|---|---|---|---|---|
Positive consistency rate (%) | 95% CI (%) | Negative consistency rate (%) | 95% CI (%) | Consistency rate (%) | 95% CI (%) | |||
HC-FIA/clinical diagnosis | Throat swabs | 87.69 | 83.08–92.30 | 95.01 | 92.82–97.20 | 92.53 | 90.38–94.68 | 0.8323 |
Sputum | 91.94 | 85.16–98.72 | 92.41 | 86.57–98.25 | 92.20 | 87.77–96.63 | 0.8419 | |
All samples | 88.61 | 84.57–92.65 | 94.92 | 92.85–96.99 | 92.69 | 90.72–94.66 | 0.8393 | |
HC-FIA/RT–qPCR | Throat swabs | 100 | 99.85–100 | 99.26 | 98.43–100 | 99.49 | 98.92–100 | 0.9883 |
Sputum | 100 | 99.74–100 | 98.73 | 96.26–100 | 99.29 | 97.90–100 | 0.9856 | |
All samples | 100 | 99.87–100 | 99.18 | 98.38–99.98 | 99.46 | 98.93–99.99 | 0.9879 | |
