Extended Data Fig. 4: iOligo-based approaches can be used to reduce cell type-specific Cas9 gene editing in models of lung inflammation. | Nature Biomedical Engineering

Extended Data Fig. 4: iOligo-based approaches can be used to reduce cell type-specific Cas9 gene editing in models of lung inflammation.

From: Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver

Extended Data Fig. 4

(a) The percentage of ICAM-2 indels in hepatocytes and (b) lung endothelial cells following treatment of Ova, iOligo / Ctrl, and sgICAM-2 / sgCtrl, *p = 0.04, **p = 0.009 one-way ANOVA, average + /- SEM.

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