Extended Data Fig. 3
From: Reduction of mtDNA heteroplasmy in mitochondrial replacement therapy by inducing forced mitophagy
CISD1-Binding recruits GFP-LC3 at different mouse-embryo stages. Mouse zygotes were microinjected with the CISD1-Binding (red) and GFP-LC3 (green) mRNA and cultured to 2-cell, 4-cell and 8-cell stages. The insets indicate that CISD1-Binding recruits GFP-LC3. Bar = 30 μm. Also, see Fig. 3a and c. Four independently repeated biological experiments with similar results.
