Extended Data Fig. 4: PD-L1 binding clones contribute to the antitumour effect of the CAR-T cell library. | Nature Biomedical Engineering

Extended Data Fig. 4: PD-L1 binding clones contribute to the antitumour effect of the CAR-T cell library.

From: Synthetic libraries of immune cells displaying a diverse repertoire of chimaeric antigen receptors as a potent cancer immunotherapy

Extended Data Fig. 4

a, Phage-displayed scFvs against murine PD-L1 were selected by 4 rounds of panning. A gradual increase in phage titers was detected after each round of panning. CFU, colony-forming unit. b, Polyclonal phage ELISA from the output phage of each round of panning. The control group used BSA as the irrelevant antigen. c. Tumour volumes of MC38 tumour xenografts after the indicated treatment. The data are represented as the mean ± s.d. (b-c).

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