Extended Data Fig. 4: Secreted IL-8 and MCP-1 levels measured in intestine-chip outflows.

a, Secreted IL-8 levels measured in the Intestine chips lower channel outflows, with and without peristalsis (P). Secreted MCP-1 levels measured in the Intestine chips lower channel outflows, with and without peristalsis. *, p < 0.03; **, p < 0.005; ***, p < 0.0002; ****, p < 0.000002. 3–6 chips for each condition. Each chip = One biological replicate. b, Differential Interference Contrast (DIC) imaging of Intestine chips, top-down view. Representative images of EED chips.