Fig. 5: Multiplexed visual detection of SARS-CoV-2 variants.
a, Detection of and discrimination among Alpha, Beta, Gamma and Delta variants. Design of origami papers (top left), photographs and GAR values of origami papers with the addition of wild SARS-CoV-2 or SARS-CoV-2 variants (bottom), and the identification of mutations in each sample (top right). A GAR value above the red dashed line indicates a positive result. b, MARVE can be customized to detect emerging SARS-CoV-2 variants within 18 d. c, Streamlined detection of SARS-CoV-2 variants. d, Equipment and consumables needed for performing MARVE. e, Streamlined detection protocols achieved detection of 400 copies per μl of SARS-CoV-2 pseudovirus. Data in e are from 2 replicates. The concentration of SARS-CoV-2 pseudovirus was 2,400 copies per μl in a.
