Table 3 Median Mtb EV levels at TB diagnosis and post initiation of TB treatment

From: Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples

 

Number of children

Pre-TBTx initiationa

Post-TBTx initiationa

P valueb

All TB cases

50

15.1 (7.5, 37.4)

4.9 (1.5, 13.4)

<0.0001

Confirmed TB

9

35.1 (9.1, 64.2)

5.3 (0.9, 13.5)

0.0056

Unconfirmed TB

41

14.0 (6.9, 35.1)

4.7 (2.1, 13.1)

0.0015

  1. IQRs are given in brackets.
  2. aMedian 5.5 months (IQR; 3.1, 5.7) between TBTx initiation and post-TBTx initiation.
  3. bPaired Wilcoxon signed-rank test (two-sided).
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