Extended Data Fig. 1: Comparison of MnFe2O4-EOB-PEG and Gd-EOB-DTPA for the detection of small liver tumours. | Nature Biomedical Engineering

Extended Data Fig. 1: Comparison of MnFe2O4-EOB-PEG and Gd-EOB-DTPA for the detection of small liver tumours.

From: A hepatocyte-targeting nanoparticle for enhanced hepatobiliary magnetic resonance imaging

Extended Data Fig. 1

a, Representative MnFe2O4-EOB-PEG and Gd-EOB-DTPA enhanced MRI of rabbit’s liver using the starvibe sequence. One rabbit was randomly implanted 5 pieces of VX2 tumours in liver. All five tumours were detected using the MnFe2O4-EOB-PEG, the tumour 4 and tumour 5 were absent on the Gd-EOB-DTPA-enhanced MRI. b, Histopathological detection of the liver VX2 tumours with sizes of 3.72 mm × 2.47 mm (tumour 1), 3.62 mm × 3.29 mm (tumour 2), 3.88 mm × 2.17 mm (tumour 3), 2.35 mm × 2.60 mm (tumour 4) and 3.13 mm × 1.82 mm (tumour 5), respectively. Scale bar, 1 mm.

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