Extended Data Fig. 9: Total traction forces of different breast-cancer cell lines. | Nature Biomedical Engineering

Extended Data Fig. 9: Total traction forces of different breast-cancer cell lines.

From: Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer

Extended Data Fig. 9

Cells were precultured on tissue culture polystyrene (PS), collagen, and mineralized collagen. Cells were precultured on the different substrates for 7 days prior to reseeding on PA gels for traction force microscopy measurements (MDA-MB231 (PS: 44 cells examined from 3 gels; Col and MN-col: at least 61 cells examined from 6 gels); MCF7 (at least 31cells examined from 5 gels); BoM-1833 (PS: 21 cells examined from 2 gels; Col and MN-col: at least 33 cells examined from 3 gels)). *p = 0.0459; **p = 0.0076; ***p = 0.0001; #p = 0.0193. Data are mean ± SD. Data were calculated using Kruskal Wallis test with Dunn’s multiple comparisons.

Source data

Back to article page